{"id":1056,"date":"2014-11-05T06:25:47","date_gmt":"2014-11-04T22:25:47","guid":{"rendered":"http:\/\/haylei.info\/%e7%89%9b%e5%a5%b6%e7%9a%84%e4%ba%8b%e5%af%a6%e8%88%87%e8%a2%ab%e6%8a%b9%e9%bb%91%ef%bc%88%e8%bd%89%e6%96%87%ef%bc%89\/"},"modified":"2022-05-17T19:28:45","modified_gmt":"2022-05-17T11:28:45","slug":"%e7%89%9b%e5%a5%b6%e7%9a%84%e4%ba%8b%e5%af%a6%e8%88%87%e8%a2%ab%e6%8a%b9%e9%bb%91%ef%bc%88%e8%bd%89%e6%96%87%ef%bc%89","status":"publish","type":"post","link":"https:\/\/haylei.info\/?p=1056","title":{"rendered":"\u725b\u5976\u7684\u4e8b\u5be6\u8207\u88ab\u62b9\u9ed1\uff08\u8f49\u6587\uff09"},"content":{"rendered":"

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 <\/p>\n

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\n

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\u725b\u4e73\u4e2d\u7684IGF-1\u6703\u81f4\u764c\uff1f<\/h3>\n

Insulin-like Growth Factor 1 \uff08IGF-1, \u985e\u80f0\u5cf6\u7d20\u751f\u9577\u56e0\u5b50\u7b2c\u4e00\u578b\uff09\uff0c\u7576\u751f\u9577\u6fc0\u7d20\u9032\u5165\u809d\u7d30\u80de\u5f8c\uff0c\u6703\u4f7f\u809d\u7d30\u80de\u5206\u6ccc IGF-1\u3002IGF-1 \u80fd\u5920\u589e\u52a0\u808c\u8089\u5f37\u5ea6\u3001\u589e\u52a0\u9aa8\u8cea\u5bc6\u5ea6\u3001\u5e6b\u52a9\u795e\u7d93\u4fee\u5fa9\u3001\u6e1b\u5c11\u81bd\u56fa\u9187\u3001\u6e1b\u8f15\u9ad8\u8840\u58d3\u75c7\u72c0\u7b49\u529f\u80fd\u3002\u6709\u7814\u7a76\u986f\u793a\u916a\u86cb\u767d\u3001IGF-1\u3001\u96c4\u6027\u6fc0\u7d20\u3001\u96cc\u6027\u6fc0\u7d20\u6703\u6709\u81f4\u764c\u98a8\u96aa\uff0c\u53c8\u725b\u4e73\u4e2d\u542b\u6709\u9019\u4e9b\u7269\u8cea\uff0c\u56e0\u6b64\u6709\u5fc3\u4eba\u58eb\u5c31\u5c07\u4e09\u8005\u5283\u4e0a\u7b49\u865f\uff0c\u725b\u4e73=\u6709\u6fc0\u7d20=\u6703\u81f4\u764c\uff0c\u9019\u5c0d\u725b\u4e73\u592a\u4e0d\u516c\u5e73\u3002<\/p>\n

\u300c\u90a3\u9ebc\u4eba\u985e\u6bcd\u4e73\u7684 IGF-1 \u542b\u91cf\u662f 2.2 ng\/mg protein\uff0c\u725b\u4e73 IGF-1 \u542b\u91cf\u5247\u662f 0.6 ng\/mg protein\uff0c\u4eba\u4e73\u662f\u725b\u4e73\u76843.6\u500d[17]\uff0c\u800c\u916a\u86cb\u767d\u5247\u662f\u666e\u904d\u5b58\u5728\u65bc\u54fa\u4e73\u52d5\u7269\u7684\u4e73\u6c41\u4e2d\uff0c\u53c8\u8a72\u5982\u4f55\u89e3\u91cb\u5462? \u300d<\/p>\n

\u7db2\u8def\u7684\u6587\u7ae0\u4e2d\u63d0\u5230\u4e86 Shen et al.<\/em> \uff082004\uff09\u9019\u7bc7\u8ad6\u6587[18]\uff0c\u4f5c\u8005\u7fa4\u70ba\u54c8\u4f5b\u5927\u5b78\u91ab\u5b78\u9662\u3001\u725b\u6d25\u5927\u5b78\u548c\u300c\u6210\u529f\u5927\u5b78\u91ab\u5b78\u9662\u300d\uff0c\u984c\u76ee\u662f\u300cIGF-1\u6703\u523a\u6fc0\u9240\u6c2f\u96e2\u5b50\u7684\u904b\u8f38\u901a\u9053\uff0c\u800c\u6b64\u904b\u8f38\u70ba\u4eba\u985e\u5375\u5de2\u764c\u548c\u5b50\u5bae\u9838\u764c\u7d30\u80de\u5165\u4fb5\u53ca\u64f4\u6563\u5fc5\u9808\u7684\u9014\u5f91\u300d\u3002\u9019\u7bc7\u6587\u7ae0\u901a\u7bc7\u300c\u5b8c\u5168\u6c92\u6709\u63d0\u5230\u4efb\u4f55\u725b\u4e73\u6216\u4e73\u88fd\u54c1\u300d\uff0c\u537b\u5c07\u725b\u4e73\u51a0\u4e0a\u6703\u81f4\u764c\u7684\u6c61\u540d\u3002\u5f15\u7528\u9019\u7bc7\u6587\u7ae0\u7684\u4f5c\u8005\u540c\u6a23\u4e5f\u662f\u72af\u4e86\u725b\u4e73\u3001IGF-1\u53ca\u81f4\u764c\u4e09\u8005\u76f4\u63a5\u756b\u4e0a\u7b49\u865f\u7684\u8b2c\u8aa4\u3002<\/p>\n

\u70ba\u4ec0\u9ebc\u4e0d\u80fd\u76f4\u63a5\u5c07\u4ed6\u5011\u756b\u4e0a\u7b49\u865f? \u9019\u5c31\u8981\u56de\u5230\u6d88\u5316\u5438\u6536\u7684\u6982\u5ff5\u3002<\/p>\n

\u6709\u7814\u7a76\u986f\u793a\u65bd\u6253 rbGH \u7684\u4e73\u725b\uff0c\u5176\u7522\u7684\u725b\u4e73\u7576\u4e2d IGF-1 \u542b\u91cf\u6703\u589e\u52a0\uff0c\u4f46\u4e0d\u7ba1\u6240\u559d\u7684\u725b\u5976\u662f\u5426\u4f7f\u7528\u904e rbGH\uff0c\u725b\u5976\u4e2d IGF-1 \u7684\u542b\u91cf\u9084\u662f\u5f88\u4f4e\u7684\u3002\u725b\u4e73\u7d93\u904e\u6d88\u5316\u3001\u5438\u6536\u4e4b\u5f8c\uff0c\u5c31\u7b97 IGF-1 \u6fc3\u5ea6\u518d\u9ad8\uff0c\u5230\u9054\u4eba\u9ad4\u5167\u4e5f\u300c\u4e0d\u518d\u5177\u6709\u751f\u7269\u5b78\u6d3b\u6027\u300d\u3002\u4ea6\u6709\u7814\u7a76\u986f\u793a\uff0c\u55ae\u7368\u53e3\u670d IGF-1 \u4e0d\u80fd\u4f7f\u5176\u9032\u5165\u8840\u6db2\uff0c\u4e14\u7528\u540c\u4f4d\u7d20\u6a19\u8a18\u6cd5\u76f4\u63a5\u6e2c\u91cf\u767c\u73fe\uff0c\u5f9e\u8178\u9053\u5438\u6536\u7684 IGF-1 \u7684\u91cf\u53ef\u4ee5\u5ffd\u7565[19][20]\u3002<\/p>\n

\u7d50\u8a9e<\/h3>\n

\u725b\u5976\u7684\u78ba\u662f\u500b\u512a\u826f\u7684\u86cb\u767d\u8cea\u4f86\u6e90\uff0c\u4f46\u51e1\u4e8b\u7269\u6975\u5fc5\u53cd\uff0c\u4efb\u4f55\u55ae\u4e00\u98df\u54c1\u98df\u7528\u904e\u591a\u90fd\u6703\u9020\u6210\u7684\u71df\u990a\u4e0d\u5747\u8861\uff0c\u56e0\u6b64\u5efa\u8b70\u5927\u5bb6\u9084\u662f\u8981\u5747\u8861\u98f2\u98df\u3002\u53e6\u5916\uff0c\u7db2\u8def\u4e0a\u5145\u65a5\u8457\u592a\u591a\u5371\u8a00\u8073\u807d\u3001\u5167\u5bb9\u4e0d\u5be6\u6216\u662f\u504f\u9817\u7684\u6587\u7ae0\uff0c\u53c8\u7db2\u8def\u4e0a\u7fd2\u6163\u5feb\u901f\u95b1\u8b80\u6587\u7ae0\u7684\u98a8\u6c23\uff0c\u9020\u6210\u8b80\u8005\u4e0d\u5bb9\u6613\u5224\u65b7\u6587\u7ae0\u5167\u5bb9\u7684\u771f\u507d\u3002\u8981\u50b3\u64ad\u81ea\u5df1\u7684\u7406\u5ff5\u975e\u5e38\u6b61\u8fce\uff0c\u4f46\u5be6\u5728\u662f\u6c92\u5fc5\u8981\u5229\u7528\u653b\u64ca\u4ed6\u4eba\u7684\u624b\u6bb5\u4f86\u9054\u6210\u76ee\u7684\u3002<\/p>\n

\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n

    \n
  1. Torfadottir JE et al<\/em>. Milk intake in early life and risk of advanced prostate cancer<\/a>. Am J Epidemiol. 2012 Jan 15;175(2):144-53. doi: 10.1093\/aje\/kwr289.<\/li>\n
  2. Song Y et al.<\/em> Whole milk intake is associated with prostate cancer-specific mortality among U.S. male physicians<\/a>. J Nutr. 2013 Feb;143(2):189-96. doi: 10.3945\/jn.112.168484.<\/li>\n
  3. Pettersson, et al. Milk and dairy consumption among men with prostate cancer and risk of metastases and prostate cancer death.<\/a> Cancer Epidemiol Biomarkers Prev. 2012 Mar;21(3):428-36. doi: 10.1158\/1055-9965.EPI-11-1004.<\/li>\n
  4. Travis RC et al. <\/a><\/em>Genetic variation in the lactase gene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition.<\/a> Int J Cancer. 2013 Apr 15;132(8):1901-10. doi: 10.1002\/ijc.27836. Epub 2012 Oct 17.<\/li>\n
  5. Ganmaa D et al.<\/em> Milk, dairy intake and risk of endometrial cancer: a 26-year follow-up<\/a>. Int J Cancer. 2012 Jun 1;130(11):2664-71. doi: 10.1002\/ijc.26265. Epub 2011 Sep 17.<\/li>\n
  6. Fei Li, Sheng-li An, You Zhou, Zhong-kun Liang, Zhan-jiang Jiao, Yu-ming Jing, Pei Wan, Xiao-jun Shi, Wan-long Tan. Milk and dairy consumption and risk of bladder cancer: a meta-analysis<\/a>. Urology. 2011 Dec;78(6):1298-305. doi: 10.1016\/j.urology.2011.09.002.<\/li>\n
  7. Sabita S Soedamah-Muthu et al. <\/em>Milk and dairy consumption and incidence of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies.<\/a> Am J Clin Nutr. Jan 2011; 93(1): 158–171. Published online Nov 10, 2010. doi: 10.3945\/ajcn.2010.29866<\/li>\n
  8. Aune D et al.<\/em> Dairy products and colorectal cancer risk: a systematic review and meta-analysis of cohort studies.<\/a> Ann Oncol. 2012 Jan;23(1):37-45. doi: 10.1093\/annonc\/mdr269. Epub 2011 May 26.<\/li>\n
  9. Jia-Yi Dong, Lijun Zhang, Ka He, Li-Qiang Qin. Dairy consumption and risk of breast cancer: a meta-analysis of prospective cohort studies.<\/a> Breast Cancer Research and Treatment. May 2011, Volume 127, Issue 1, pp 23-31<\/li>\n
  10. Berkey CS et al. <\/em>Dairy intakes in older girls and risk of benign breast disease in young women. <\/a>Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):670-4. doi: 10.1158\/1055-9965.EPI-12-1133. Epub 2013 Mar 29.<\/li>\n
  11. Merritt MA et al.<\/em> Dairy food and nutrient intake in different life periods in relation to risk of ovarian cancer.<\/a> Cancer Causes Control. 2014 Jul;25(7):795-808. doi: 10.1007\/s10552-014-0381-7. Epub 2014 Apr 11.<\/li>\n
  12. Tracy E. Crane et al.<\/em> Dietary Intake and Ovarian Cancer Risk: A Systematic Review.<\/a> Cancer Epidemiol Biomarkers Prev. 2014 Feb;23(2):255-73. doi: 10.1158\/1055-9965.EPI-13-0515. Epub 2013 Oct 18.<\/li>\n
  13. Choi et al<\/em>. Dairy Consumption and Risk of Type 2 Diabetes Mellitus in Men.<\/a> Arch Intern Med. 2005;165(9):997-1003. doi:10.1001\/archinte.165.9.997.<\/li>\n
  14. Van Belle et al. Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies<\/a>. PPhysiol Rev 91: 79–118, 2011; doi:10.1152\/physrev.00003.2010.<\/li>\n
  15. Struijk EA et al.<\/em> Dairy product intake in relation to glucose regulation indices and risk of type 2 diabetes.<\/a> Nutr Metab Cardiovasc Dis. 2013 Sep;23(9):822-8. doi: 10.1016\/j.numecd.2012.05.011. Epub 2012 Jul 23.<\/li>\n
  16. O’Connor LM et al. Dietary dairy product intake and incident type 2 diabetes: a prospective study using dietary data from a 7-day food diary<\/a>. Diabetologia. 2014 May;57(5):909-17. doi: 10.1007\/s00125-014-3176-1. Epub 2014 Feb 8.<\/li>\n
  17. Nagashima K et al.<\/em> Levels of insulin-like growth factor I in full- and preterm human milk in comparison to levels in cow’s milk and in milk formulas. Biol Neonate.<\/a> 1990;58(6):343-6.<\/li>\n
  18. Meng-Ru Shen et al.<\/em> Insulin-like Growth Factor 1 Stimulates KCl Cotransport, Which Is Necessary for Invasion and Proliferation of Cervical Cancer and Ovarian Cancer Cells.<\/a> J Biol Chem. 2004 Sep 17;279(38):40017-25. Epub 2004 Jul 19.<\/li>\n
  19. Burrin DG et al.<\/em> Is milk-borne insulin-like growth factor-I essential for neonatal development? <\/a>J Nutr. 1997 May;127(5 Suppl):975S-979S.<\/li>\n
  20. Donovan SM et al.<\/em> Orally administered iodinated recombinant human insulin-like growth factor-I (125I-rhIGF-I) is poorly absorbed by the newborn piglet<\/a>. J Pediatr Gastroenterol Nutr. 1997 Feb;24(2):174-82.<\/li>\n
  21. \u6c88\u83ef\u5c71\u3002\u4e73\u54c1\u52a0\u5de5\u5b78<\/li>\n
  22. \u3008\u725b\u4e73\u4e0d\u8a72\u4e00\u5473\u53d7\u8ca0\u9762\u65b0\u805e\u6328\u6253<\/a>\u3009\u4e2d\u83ef\u6c11\u570b\u4e73\u696d\u5354\u6703 \u3002[ 2012\/3\/16]<\/li>\n
  23. \u5f90\u6fdf\u6cf0\u3002\u3008\u725b\u4e73\u5230\u5e95\u80fd\u4e0d\u80fd\u559d\uff1f<\/a>\u3009\u81fa\u5927\u8fb2\u696d\u63a8\u5ee3\u901a\u8a0a\u96d9\u6708\u520a91\u671f<\/li>\n
  24. \u3008\u725b\u5976\u81f4\u764c\uff1f<\/a>\u3009\u6cdb\u79d1\u5b78[2013\/11\/29]<\/li>\n<\/ol>\n

    \u672c\u6587\u8f49\u8f09\u81ea\u4f60\u6240\u4e0d\u77e5\u9053\u7684\u755c\u7522<\/a><\/p>\n

    \n

    About Author<\/h2>\n<\/div>\n

    \"\u725b\u5976\u7684\u4e8b\u5be6\u8207\u88ab\u62b9\u9ed1\uff08\u8f49\u6587\uff09<\/p>\n

    \u6d3b\u8e8d\u661f\u7cfb\u6838<\/a><\/h3>\n

    \u6d3b\u8e8d\u661f\u7cfb\u6838\uff08active galactic nucleus, AGN\uff09\u662f\u4e00\u985e\u4e2d\u592e\u6838\u5340\u6d3b\u52d5\u6027\u5f88\u5f37\u7684\u6cb3\u5916\u661f\u7cfb\u3002\u9019\u4e9b\u661f\u7cfb\u6bd4\u666e\u901a\u661f\u7cfb\u6d3b\u8e8d\uff0c\u5728\u5f9e\u7121\u7dda\u96fb\u6ce2\u5230\u4f3d\u746a\u5c04\u7dda\u7684\u5168\u6ce2\u6bb5\u88e1\u90fd\u767c\u51fa\u5f88\u5f37\u7684\u96fb\u78c1\u8f3b\u5c04\u3002 \u672c\u5e33\u865f\u767c\u8868\u4f86\u81ea\u5404\u65b9\u7684\u6295\u7a3f\u3002\u9644\u6709\u8cc7\u6599\u51fa\u8655\u7684\u79d1\u5b78\u597d\u6587\uff0c\u90fd\u6b61\u8fce\u4f60\u4f86\u6295\u7a3f\u5594\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

    \u725b\u5976\u7684\u4e8b\u5be6\u8207\u88ab\u62b9\u9ed1\uff08\u8f49\u6587\uff09   \u6700\u8fd1\u62d2\u8cb7\u6797\u9cf3\u71df\u7684\u4e8b\u4ef6\u7d1b\u7d1b\u8d77\u98db\uff0c\u53c8\u958b\u59cb\u6709\u5c0d\u4e73\u54c1\u7684\u7591\u7fa9\uff0c\u4e0d\u904e\u6211\u5011\u662f\u56e0\u70ba\u5b83 […] <\/p>\n

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